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When the body undergoes stress, cortisol, a glucocorticoid, is released from the adrenal cortex in response. As a result, the immune system is weakened which is why people often get sick when they're stressed because the body has redirected it's functional importance to the cause of stress. The body is more concerned with restoring the body to homeostasis or responding in a fight-or-flight method instead of immune function.
Contributed by Lauren Bandyk