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Lophophora williamsii /lˈfɒfərə wɪlˈjæmsi/ or peyote (/pəˈjti/) is a small, spineless cactus with psychoactive alkaloids, particularly mescaline. The English common name peyote is a Spanish loanword, which comes from the Nahuatl name peyōtl [ˈpejoːt͡ɬ], said to be derived from a root meaning "glisten" or "glistening". Other sources translate the Nahuatl word as "Divine Messenger"."Empiricism and Magic in Aztec Pharmacology", Efren C. del Pozo, Instituto de Estudios Medicos y Biologicos National, University of Mexico, in book "Ethnopharmacologic Search for PSYCHOACTIVE DRUGS", publisher: Pharmacology Section, Psychopharmacology Research Branch National Institute of Mental Health Public Health Service, U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE, U.S. Government Printing Office Native North Americans are likely to have used peyote, often for spiritual purposes, for at least 5,500 years.

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A documentary about sacred peyote and its early use, origins, and effects.

Contributed by Sammo Lea

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