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The West African Ebola virus epidemic (2013–2016) was the most widespread outbreak of Ebola virus disease (EVD) in history—causing major loss of life and socioeconomic disruption in the region, mainly in the countries of Guinea, Liberia, and Sierra Leone. The first cases were recorded in Guinea in December 2013; later, the disease spread to neighboring Liberia and Sierra Leone, while the rate among hospitalized patients was 57–59%. Small outbreaks occurred in Nigeria and Mali, and isolated cases were recorded in Senegal, the United Kingdom and Sardinia. In addition, imported cases led to secondary infection of medical workers in the United States and Spain but did not spread further. The number of cases peaked in October 2014 and then began to decline gradually, following the commitment of substantial international resources. , the World Health Organization (WHO) and respective governments reported a total of 28,616 suspected cases and 11,310 deaths (39.5%), though the WHO believes that this substantially understates the magnitude of the outbreak.
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